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KMID : 0604520060320030181
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Journal of the Society of Cosmetic Scientists of Korea
2006 Volume.32 No. 3 p.181 ~ p.191
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Antioxidative and Cellular Protective Effects of Jeju Native Plant Extracts against Reactive Oxygen Species (I)
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Park Soo-Nam
Choi Jung-Won
Kim So-I
Jeon So-Mi
Kim Jin-Young
Yang Hee-Jung
Lee Keun-Ha
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Abstract
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In this study, we investigated the anti-oxidative, anti-wrinkle and whitening effects of 36 plant extracts collected from self-growing plants in Jeju island. Their anti-oxidant activities were measured by free radical scavenging activity using DPPH (1,1-diphenyl-2-picrylhydrazyl radical), reactive oxygen species (ROS) scavenging activities on ROS generated in Fe^{3+}-EDTA/H_2O_2 system using the luminol-dependent chemiluminescence assay, and cell protecting activities using the rose-bengal sensitized photohemolysis of human erythrocytes. In addition, the inhibitory activities of tyrosinase for whitening effect and elastase for anti-wrinkle were investigated. The results showed that the Rumex crispus (all grass) extract has the most significant free radical scavenging activity (FSC_{50};;10{mu}g/mL), Plantago asiatica and Rumex crispus extracts for the prominent ROS scavenging activity (OSC_{50};;0.006{mu}g/mL, 0.04{mu}g/mL respectively), Rumex crispus (tau_{50};;1,140 min at 50{mu}g/mL), Machilus thunbergii leaf (216 min), and Celastrus orbiculatus (200 min) for cell protecting effects, Morus alba stem for the inhibitory activity on tyrosinse (94.8% at 200{mu}g/mL), Rumex crispus (81.8% at 200{mu}g/mL), Morus alba (74.6%), and Celastrus orbiculatus leaf/stem/flower (63.1%) for the activity on elastase. These results indicated that the extracts of Rumex crispus, Plantago asiatica, Machilus thunbergii leaf, Morus alba stem, Celastrus orbiculatus leaf/stem/flower could have the functional effects when they are added as ingredients in cosmetics. Thus, it is concluded that further experiments are needed to apply for cosmetic products.
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KEYWORD
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ROS, Photohemolysis, Jeju island native plants, anti-oxidant, tyrosinase, elastase, cosmetics
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